NCT07148622View on ClinicalTrials.gov

Effects of Different Antibiotic Regimens in Preterm Premature Rupture of Membranes

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

August 1, 2025

Study Completion Date

August 10, 2025

Conditions
Preterm Premature Rupture of Membranes (PPROM)ProphylaxisPerinatal Outcomes
Interventions
DRUG

Antibiotic regimen 1: sulbactam + ampicillin + azithromycin

For the first 48 hours, 4×2 g IV sulbactam + ampicillin, 1 g oral azithromycin on day 1, and from days 3-7, 3×500 mg oral amoxicillin

DRUG

Antibiotic regimen 2: ceftriaxone + clarithromycin + amoxicillin

For the first 48 hours, 1×1 g IV ceftriaxone + 2×500 mg oral clarithromycin, and from day 3 onwards, 3×500 mg oral amoxicillin + 2×500 mg oral clarithromycin.

Trial Locations (1)

65100

Van Yuzuncu Yil University, Van

All Listed Sponsors
lead

Yuzuncu Yıl University

OTHER

NCT07148622 - Effects of Different Antibiotic Regimens in Preterm Premature Rupture of Membranes | Biotech Hunter | Biotech Hunter