Sentinel Lymph Node Detection in Gastric Cancer Using a Dual Tracer (Superparamagnetic Iron Oxide and Methylene Blue): A Prospective Study With Histological and OSNA Validation

Active, not recruitingOBSERVATIONAL
Enrollment

44

Participants

Timeline

Start Date

August 1, 2017

Primary Completion Date

August 1, 2025

Study Completion Date

August 31, 2025

Conditions
Gastric Cancer (GC)Sentinel Lymph Node Biopsy (SLNB)
Interventions
PROCEDURE

Dual tracer: The infiltration of the Supermagnetic Iron Oxide (SPIO) and Methylene Blue

"Participation in the study did not alter the indications or standard surgical technique. The only additional intervention consisted of intraoperative administration of SPIO, performed either laparoscopically or conventionally, as appropriate.~Immediately after removal of the surgical specimen : Submucosal instillation of methylene blue was then performed at the tumour periphery"

DIAGNOSTIC_TEST

OSNA AND H-E

Analysed the performance of one-step nucleic acid amplification (OSNA) versus conventional histology and applied pooling analysis with OSNA in non-sentinel nodes

Trial Locations (1)

11403

Univesrsity Hospital of Jerez Frontera, Jerez de la Frontera

All Listed Sponsors
collaborator

Sysmex España

INDUSTRY

lead

Hospital del SAS de Jerez

OTHER