A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop

PHASE3Not yet recruitingINTERVENTIONAL

Enrollment

922

Participants

Timeline

Start Date

October 13, 2025

Primary Completion Date

February 20, 2029

Study Completion Date

December 31, 2029

Conditions

Rheumatic Heart Disease

Interventions

DRUG

Secondary Prophylaxis

Continue standard of care with continued secondary antibiotic prophylaxis

All Listed Sponsors

collaborator

Uganda Heart Institute

OTHER

lead

Children's Hospital Medical Center, Cincinnati

OTHER