Moxidectin Versus Ivermectin as Mass Drug Administration for the Control of Onchocerciasis and Other Neglected Tropical Diseases: A Cluster-randomised Trial

PHASE4RecruitingINTERVENTIONAL
Enrollment

52,000

Participants

Timeline

Start Date

August 4, 2025

Primary Completion Date

March 31, 2029

Study Completion Date

June 30, 2029

Conditions
OnchocerciasisAscaris Lumbricoides InfectionTrichuris Trichiura; InfectionHookworm InfectionsScabies
Interventions
DRUG

Moxidectin

2 mg tablets

DRUG

Ivermectin

3 mg tablets

Trial Locations (1)

Unknown

RECRUITING

Villages in Andulo and Nharea Municipalities, Andulo

All Listed Sponsors
collaborator

Emory University

OTHER

collaborator

La Trobe University

OTHER

collaborator

Murdoch Childrens Research Institute

OTHER

collaborator

Medicines Development for Global Health

OTHER

collaborator

University of Melbourne

OTHER

collaborator

Swiss Tropical & Public Health Institute

OTHER

collaborator

University of Ottawa

OTHER

collaborator

The Mentor Initiative

OTHER

collaborator

Erasmus Medical Center

OTHER

collaborator

Ministry of Health, Angola

UNKNOWN

collaborator

The END Fund

UNKNOWN

collaborator

Center for Research on Filariasis and Other Tropical Diseases, Cameroon

OTHER

collaborator

World Health Organization

OTHER

lead

Kirby Institute

OTHER_GOV