Induced Pluripotent Stem Cells-derived Small Extracellular Vesicles May Promote Neurological Function and Improve Cognitive Impairment in Acute Ischemic Stroke Patients

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

March 7, 2025

Primary Completion Date

July 30, 2025

Study Completion Date

January 1, 2026

Conditions
Cognitive Impairment
Interventions
BIOLOGICAL

iEV

Intranasal administration of iEV, twice a week, 2 ml each time (at a concentration of 2×10¹⁰/ml), for 12 consecutive weeks.

OTHER

Basic treatments

Basic treatments for cerebrovascular diseases such as antiplatelet aggregation, blood pressure control, blood glucose control, blood lipid control, and plaque stabilization.

Trial Locations (1)

200000

RECRUITING

Shanghai Sixth People's Hospital, Shanghai

All Listed Sponsors
lead

Hongmei Wang

OTHER