NCT07144826View on ClinicalTrials.gov

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

EARLY_PHASE1Not yet recruitingINTERVENTIONAL
Enrollment

161

Participants

Timeline

Start Date

September 9, 2025

Primary Completion Date

July 9, 2026

Study Completion Date

July 9, 2026

Conditions
Advanced Ovarian CarcinomaRecurrent Ovarian CarcinomaStage II Ovarian Cancer AJCC v8Stage III Ovarian Cancer AJCC v8Stage IV Ovarian Cancer AJCC v8
Interventions
PROCEDURE

Biospecimen Collection

Undergo blood and vaginal sample collection

DRUG

Placebo Administration

Given PO

DIETARY_SUPPLEMENT

Probiotic

Given PO

OTHER

Questionnaire Administration

Ancillary studies

Trial Locations (1)

43210

Ohio State University Comprehensive Cancer Center, Columbus

All Listed Sponsors
lead

Ohio State University Comprehensive Cancer Center

OTHER