Efficacy of 810 nm Diode Laser Disinfection on Inflammatory Cytokines and Postoperative Pain After Endodontic Retreatment

NARecruitingINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

August 18, 2025

Primary Completion Date

September 15, 2026

Study Completion Date

October 20, 2026

Conditions
Previous Endodontic Treatment Failure and Radiographically Confirmed Periapical Radiolucency
Interventions
DEVICE

810 nm diode laser disinfection

810 nm diode laser (Elexxion clarosdental laser, Singen Deutschland, Germany) in a continuous wave mode with a power of 1.5 Watts in 4 cycles of 5 seconds with 20 seconds intervals in between each. A 200 μm fiber optic tip (Lite medics, Italy) will be inserted 1 mm from the working length, activated and moved in slow helical motion from the apex to the cervical third with alternating between clockwise and counterclockwise direction at speed of about 2 mm/s

DRUG

Calcium Hydroxide Intracanal medication

Calcium hydroxide paste (MetaBiomed, Chungcheongbuk-do, Korea) will be placed inside the root canal and left for 1 week.

Trial Locations (1)

Unknown

RECRUITING

from the outpatient clinic of Endodontic Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo

All Listed Sponsors
lead

Al-Azhar University

OTHER

NCT07141459 - Efficacy of 810 nm Diode Laser Disinfection on Inflammatory Cytokines and Postoperative Pain After Endodontic Retreatment | Biotech Hunter | Biotech Hunter