Clinical Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics of HSK31858 in Healthy Subjects

PHASE1Enrolling by invitationINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

August 11, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2026

Conditions
Healthy Subjects
Interventions
DRUG

HSK31858 Tablets and Itraconazole Capsules

"HSK31858 Tablets On the morning of Day 1, a single dose of HSK31858 tablets 40 mg will be administered.~Itraconazole capsules After a 10-day washout period, Take Itraconazole capsules 200mg in the morning and 200mg in the evening on D11 . A single dose of Itraconazole capsules 200 mg will be administered every morning from Day 12 to Day 14. On the morning of Day 15, take a single dose of itraconazole capsules 200mg, followed by a single dose of HSK31858 tablets 40 mg 1 hour later,"

Trial Locations (1)

Unknown

Renji Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai

All Listed Sponsors
lead

Haisco Pharmaceutical Group Co., Ltd.

INDUSTRY