Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

October 31, 2025

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
DemineralizationRemineralizationDental CavityEnamel Lesions
Interventions
DRUG

Fluoride free toothpaste in a chalk base

Fluoride free toothpaste in a chalk base with herbal ingredients

DRUG

Fluoride Toothpaste

Fluoride toothpaste containing 1000 ppm MFP and 1.5% arginine in a PCC/RNCC base

DRUG

Fluoride free toothpaste in a PCC/RNCC base

Fluoride free toothpaste in a PCC/RNCC base

DEVICE

Toothbrush

A commercially available adult soft bristle toothbrush

Trial Locations (1)

57072-970

Federal University of Alagoas, Maceió

All Listed Sponsors
collaborator

Federal University of Alagoas

OTHER

lead

Colgate Palmolive

INDUSTRY