NCT07130786View on ClinicalTrials.gov

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

PHASE2Not yet recruitingINTERVENTIONAL

Enrollment

150

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

February 28, 2029

Study Completion Date

February 28, 2030

Conditions

SeizuresPrimary Motor CortexBrain Metastases From Non-small Cell Lung Cancer (NSCLC)Brain Metastases, AdultBrain Metastases From Extra-cranial Solid Tumors

Interventions

DRUG

Levetiracetam (Keppra)

Patients will be randomized to receive levetiracetam/ASM or to receive no ASM therapy

Trial Locations (1)

02115

Brigham and Women's Hospital, Boston

All Listed Sponsors

lead

Ayal A. Aizer, MD

OTHER