Endotracheal Suctionning During Positive Pressure Extubation in ICU

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

September 30, 2027

Study Completion Date

October 31, 2027

Conditions
Mechanical Ventilation With Oral IntubationWeaning Invasive Mechanical VentilationOxygen Saturation MeasurementRox IndexExtubation
Interventions
PROCEDURE

Suctionning extubation

We will remove the intubation tube with endotracheal suctioning during the extubation procedure and maintain positive end expiratory pressure (PEEP) and pressure support. The PEEP level will be 10 cmH2O and the pressure support 7 cmH2O for 2 minutes prior to extubation. The vacuum level will be the maximum level (standard procedure in the unit), i.e. 450 mmHg. The closed-system suction probe is inserted up to the last mark corresponding to 40cm. The size of our closed system is identical for all patients, i.e. 14 french.

PROCEDURE

No suctionning Extubation

In the control group, removal of the intubation tube during the extubation procedure is performed with PEEP maintained, without endotracheal suctioning. The PEEP level will be set at 10 cmH2O and the pressure at 7 cmH2O in the 2 minutes prior to extubation.

Trial Locations (1)

45067

Centre Hospitalier Universitaire d'Orléans, Orléans

All Listed Sponsors
lead

Centre Hospitalier Régional d'Orléans

OTHER

NCT07130123 - Endotracheal Suctionning During Positive Pressure Extubation in ICU | Biotech Hunter | Biotech Hunter