NCT07128953View on ClinicalTrials.gov

Study on the Mechanism of Zuoqing San Promoting Postoperative Wound Healing of Anal Fistula by Inhibiting ROS-dependent NETosis

EARLY_PHASE1Enrolling by invitationINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

August 2, 2025

Study Completion Date

February 1, 2026

Conditions
Anal Fistula
Interventions
DRUG

Solution of Zuoqing San for fumigation and washing of the postoperative wound of anal fistula

Left Qing San Decoction (25g of Cai Yin + 30g of Eucommia + 25g of Sophora flavescens + 25g of Anemarrhena asphodeloides + 15g of Lithospermum erythrorhizon, prepared in the Pharmacy Department of Anhui University of Traditional Chinese Medicine), add 1000mL of water, boil, then steam and wash the wound surface. The temperature is 40 ± 2℃. Do it once a day, for 15 minutes each time, for 7 consecutive days.

OTHER

Equal-volume placebo inhalation rinse

Equal-volume placebo inhalation rinse

Trial Locations (1)

230000

Anhui university of Chinese Medicine, Hefei

All Listed Sponsors
lead

The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine

OTHER