Opioidergic and Noradrenergic Systems in Central Parkisonian Pain

NANot yet recruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

October 1, 2025

Primary Completion Date

October 1, 2025

Study Completion Date

October 1, 2025

Conditions
Parkinson Disease
Interventions
OTHER

PET-MRI exam with administration of [11C]Carfentanil

Recording of functional neuroimaging data will begin immediately after intravenous injection of \[11C\]Carfentanil and will last for 51 minutes in a resting state. The dose will be 250 MBq/kg +-10 %.

OTHER

PET-MRI exam with administration of [11C]Yohimbine

Recording of functional neuroimaging data will begin immediately after intravenous injection of \[11C\]Yohimbine and will last for 70 minutes in a resting state. The dose will be 370 MBq/kg +- 10 %.

Trial Locations (3)

31059

CHU de Toulouse - Hôpital Purpan, Toulouse

63003

CHU de Clermont-Ferrand Hôpital Gabriel Montpied, Clermont-Ferrand

69677

Hôpital Neurologique Pierre Wertheimer, Bron

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER