Thoracic Paravertebral Block vs Intrathecal Morphine in VATS

NARecruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

August 18, 2025

Primary Completion Date

January 1, 2026

Study Completion Date

February 1, 2026

Conditions
Postoperative Acute PainVideo-Assisted Thoracoscopic SurgeryIntrathechal MorphineParavertebral Peripheral Nerve Block
Interventions
PROCEDURE

Thoracic paravertebral block

Ultrasound-guided single-injection thoracic paravertebral block using 0.4 mL/kg of 0.25% bupivacaine with epinephrine (1:400,000) before induction of standardized general anesthesia. Postoperative analgesia will be provided with intravenous patient-controlled analgesia morphine, along with scheduled paracetamol and NSAIDs.

DRUG

Morphine

Single intrathecal injection of morphine (5 mcg/kg diluted in 3 mL 0.9% saline) at the L3-L4 or L4-L5 interspace before induction of standardized general anesthesia. Postoperative analgesia will be provided with intravenous patient-controlled analgesia morphine, along with scheduled paracetamol and NSAIDs.

Trial Locations (1)

55139

RECRUITING

Department of Anesthesiology, Faculty of Medicine, Ondokuz Mayis University, Samsun

All Listed Sponsors
lead

Ondokuz Mayıs University

OTHER

NCT07126483 - Thoracic Paravertebral Block vs Intrathecal Morphine in VATS | Biotech Hunter | Biotech Hunter