Sore Throat After Open Neck Elective Surgery

PHASE4RecruitingINTERVENTIONAL
Enrollment

764

Participants

Timeline

Start Date

September 15, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

May 31, 2027

Conditions
Postoperative Sore Throat, Cough, HoarsenessThyroid and Parathyroid Surgery
Interventions
DRUG

Hydrocortisone Acetate 1% Ointment

Endotracheal tubes will be coated with 1% hydrocortisone acetate ointment prior to intubation. The ointment will be applied uniformly to the outer surface of the tube. This intervention aims to reduce postoperative throat inflammation and pain.

DRUG

Lidocaine hydrochloride 0,05% with chlorhexidine

Endotracheal tubes will be treated with 0.05% lidocaine hydrochloride solution combined with chlorhexidine (Cathejell). The solution will be applied to the tube surface before intubation to provide local anesthesia and reduce postoperative throat discomfort.

Trial Locations (1)

Unknown

RECRUITING

Saint Petersburg State University Hospital, Saint Petersburg

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Smooth Drug Development

UNKNOWN

lead

Saint Petersburg State University, Russia

OTHER