Effect of Intracanal Medicaments on Post-Operative Pain in Symptomatic Apical Periodontitis: An RCT

NACompletedINTERVENTIONAL
Enrollment

480

Participants

Timeline

Start Date

June 3, 2024

Primary Completion Date

May 3, 2025

Study Completion Date

June 3, 2025

Conditions
Periodontal Diseases
Interventions
DRUG

Calcium Hydroxide (20%)

A 20% calcium hydroxide paste will be placed as an intracanal medicament following root canal instrumentation. Applied using a Lentulo spiral, excess is removed, and the tooth is sealed with a glass ionomer temporary restoration.

DRUG

Chlorhexidine Gel (2%)

A 2% chlorhexidine gel will be used as an intracanal medicament following canal preparation. It will be delivered with a Lentulo spiral, cleaned from the chamber, and the tooth sealed.

DRUG

Modified Triple Antibiotic Paste

A modified triple antibiotic paste consisting of ciprofloxacin, metronidazole, and clindamycin (1:1:1 by weight) will be placed in the canal using a Lentulo spiral. The excess paste will be removed, and the cavity will be sealed with temporary restorative material.

Trial Locations (1)

Unknown

Dental hospial, Hitec-IMS, Rawalpindi

All Listed Sponsors
lead

HITEC-Institute of Medical Sciences

OTHER

NCT07123792 - Effect of Intracanal Medicaments on Post-Operative Pain in Symptomatic Apical Periodontitis: An RCT | Biotech Hunter | Biotech Hunter