Traditional Chinese Medicine Intervention for Ischemic Cerebrovascular Disease and Diabetes Mellitus: An Efficacy Comparative Study

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

3,666

Participants

Timeline

Start Date

August 31, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
Ischemic Cerebral InfarctionDiabetes Mellitus
Interventions
DRUG

(Intensive treatment) Chuanzhi Tongluo Capsules

4 capsules each time, orally, 3 times a day; administration from day 1 to day 14 of the disease.

OTHER

Standard Treatment (Guideline-Based)

Combination therapy including: 1. Antiplatelet: aspirin 100 mg/day + clopidogrel 75 mg/day. 2. Lipid-lowering: atorvastatin 20 mg/day. 3. Antidiabetic: metformin 500 mg bid (max 2000 mg/day). \*Doses may be adjusted per local guidelines or patient tolerance.

DRUG

(Sequential treatment) Chuanzhi Tongluo Capsules

2 capsules each time, orally, 3 times a day; administration from day 15 to day 365.

DRUG

TCM Syndrome Differentiation Decoction

Individualized herbal decoction based on TCM diagnosis (four diagnostic methods), administered for 14 days during intensive phase.

All Listed Sponsors
lead

Guangzhou University of Traditional Chinese Medicine

OTHER