Vegan Whey Protein for Muscle Anabolism and Post-exercise Recovery

NACompletedINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

September 1, 2023

Primary Completion Date

November 22, 2024

Study Completion Date

November 22, 2024

Conditions
Muscle Soreness
Interventions
OTHER

Stable isotope tracer consumption

Daily consumption of oral deuterium oxide (0.3 ml per kg of lean body mass) to equilibrate in body water and become slowly incorporated into muscle protein, enabling measurement of muscle protein synthesis rates

RADIATION

DXA scan

Whole body DXA scan to assess lean body mass for prescription of deuterium oxide tracer

BEHAVIORAL

Controlled diet

Participant will be asked to consume a provided 6-day diet package that will be prepared by the research team. This package will include 3 meals per day plus snacks

OTHER

Saliva sample

Obtained from participants by asking them to spit into a tube each day during the study, for 11 days in total.

OTHER

Blood sample

Resting venous blood sample from a forearm vein on 6 separate occasions

PROCEDURE

Muscle biopsy

A highly experienced researcher will sample a small section of muscle (\~200 mg) from the vastus lateralis muscle under local anaesthetic (5 ml, 1% Lidocaine)

BEHAVIORAL

Resistance exercise

participants will complete 8 sets of 10 repetitions of unilateral eccentric knee extensions on an isokinetic dynamometer.

OTHER

Isometric strength test

Bilateral isometric strength will be measured using a well-established protocol on an isokinetic dynamometer.

DIETARY_SUPPLEMENT

Supplement

Consumption of 3 supplements a day for 3 days following resistance exercise. All supplements are commercially available.

Trial Locations (1)

B15 2TT

School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham

All Listed Sponsors
lead

University of Birmingham

OTHER

NCT07119749 - Vegan Whey Protein for Muscle Anabolism and Post-exercise Recovery | Biotech Hunter | Biotech Hunter