Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)

PHASE3RecruitingINTERVENTIONAL
Enrollment

3,040

Participants

Timeline

Start Date

September 22, 2025

Primary Completion Date

January 16, 2031

Study Completion Date

January 16, 2031

Conditions
Plaque Psoriasis
Interventions
DRUG

Deucravacitinib

Specified dose on specified days

DRUG

Ustekinumab

Specified dose on specified days

Trial Locations (280)

100

NOT_YET_RECRUITING

Local Institution - 0303, Taipei

1033

NOT_YET_RECRUITING

Local Institution - 0209, Budapest

1199

NOT_YET_RECRUITING

Local Institution - 0453, Autonomous City of Buenos Aires

1200

NOT_YET_RECRUITING

Local Institution - 0063, Woluwe-Saint-Lambert

1404

NOT_YET_RECRUITING

Local Institution - 0487, Sofia

1527

NOT_YET_RECRUITING

Local Institution - 0484, Sofia

2010

NOT_YET_RECRUITING

Local Institution - 0271, Darlinghurst

2145

NOT_YET_RECRUITING

Local Institution - 0216, Westmead

2217

NOT_YET_RECRUITING

Local Institution - 0152, Kogarah

2400

NOT_YET_RECRUITING

Local Institution - 0196, Copenhagen

2730

NOT_YET_RECRUITING

Local Institution - 0457, Herlev

2900

NOT_YET_RECRUITING

Local Institution - 0290, Hellerup

3002

NOT_YET_RECRUITING

Local Institution - 0103, East Melbourne

3053

NOT_YET_RECRUITING

Local Institution - 0282, Carlton

3168

NOT_YET_RECRUITING

Local Institution - 0345, Clayton

4000

NOT_YET_RECRUITING

Local Institution - 0483, Plovdiv

NOT_YET_RECRUITING

Local Institution - 0486, Plovdiv

4026

NOT_YET_RECRUITING

Local Institution - 0266, Debrecen

4102

NOT_YET_RECRUITING

Local Institution - 0285, Woolloongabba

NOT_YET_RECRUITING

Local Institution - 0311, Woolloongabba

5500

NOT_YET_RECRUITING

Local Institution - 0280, Mendoza

NOT_YET_RECRUITING

Local Institution - 0480, Lovech

5800

NOT_YET_RECRUITING

Local Institution - 0479, Pleven

6003

NOT_YET_RECRUITING

Local Institution - 0485, Stara Zagora

6720

NOT_YET_RECRUITING

Local Institution - 0206, Szeged

7002

NOT_YET_RECRUITING

Local Institution - 0482, Rousse

8000

NOT_YET_RECRUITING

Local Institution - 0481, Burgas

8200

NOT_YET_RECRUITING

Local Institution - 0324, Aarhus

NOT_YET_RECRUITING

Local Institution - 0404, Veszprém

9000

NOT_YET_RECRUITING

Local Institution - 0239, Ghent

10023

NOT_YET_RECRUITING

Local Institution - 0437, New York

10117

NOT_YET_RECRUITING

Local Institution - 0291, Berlin

11415

NOT_YET_RECRUITING

Local Institution - 0028, Kew Gardens

13086

NOT_YET_RECRUITING

Local Institution - 0476, Berlin

13496

NOT_YET_RECRUITING

Local Institution - 0065, Seongnam-si, Gyeonggi-do

13620

NOT_YET_RECRUITING

Local Institution - 0067, Seongnam-si

14080

NOT_YET_RECRUITING

Local Institution - 0465, Mexico City

15238

NOT_YET_RECRUITING

Local Institution - 0095, Pittsburgh

15831

NOT_YET_RECRUITING

Local Institution - 0299, Mahlow

19341

WITHDRAWN

Local Institution - 0131, Exton

20095

NOT_YET_RECRUITING

Local Institution - 0471, Hamburg

20746

WITHDRAWN

Local Institution - 0334, Washington D.C.

20850

NOT_YET_RECRUITING

Local Institution - 0331, Rockville

21100

NOT_YET_RECRUITING

Local Institution - 0467, Mexicali

23502

WITHDRAWN

Local Institution - 0333, Norfolk

24148

NOT_YET_RECRUITING

Local Institution - 0340, Kiel

27516

NOT_YET_RECRUITING

Local Institution - 0332, Chapel Hill

27517

WITHDRAWN

Local Institution - 0165, Chapel Hill

27518

NOT_YET_RECRUITING

Local Institution - 0076, Cary

28405

NOT_YET_RECRUITING

Local Institution - 0189, Wilmington

28922

WITHDRAWN

Local Institution - 0242, Alcorcón

29405

WITHDRAWN

Local Institution - 0418, North Charleston

29615

WITHDRAWN

Local Institution - 0422, Greenville

31350

NOT_YET_RECRUITING

Local Institution - 0466, Chihuahua City

31406

NOT_YET_RECRUITING

Local Institution - 0419, Savannah

32751

NOT_YET_RECRUITING

Local Institution - 0478, Maitland

33014

WITHDRAWN

Local Institution - 0029, Miami Lakes

33133

RECRUITING

Miami Dermatology and Laser Research, Miami

33134

NOT_YET_RECRUITING

Local Institution - 0105, Coral Gables

33135

RECRUITING

International GCC Research, Miami

33615

NOT_YET_RECRUITING

Local Institution - 0089, Tampa

35000

WITHDRAWN

Local Institution - 0217, Rennes

35019

NOT_YET_RECRUITING

Local Institution - 0337, Las Palmas de Gran Canaria

35249

NOT_YET_RECRUITING

Local Institution - 0088, Birmingham

40138

NOT_YET_RECRUITING

Local Institution - 0307, Bologna

41009

NOT_YET_RECRUITING

Local Institution - 0236, Seville

41126

NOT_YET_RECRUITING

Local Institution - 0305, Modena

42104

NOT_YET_RECRUITING

Local Institution - 0435, Bowling Green

42301

WITHDRAWN

Local Institution - 0030, Owensboro

44093

NOT_YET_RECRUITING

Local Institution - 0238, Nantes

44638

NOT_YET_RECRUITING

Local Institution - 0321, Guadalajara

44718

NOT_YET_RECRUITING

Local Institution - 0492, Canton

45190

NOT_YET_RECRUITING

Local Institution - 0470, Zapopan

46256

NOT_YET_RECRUITING

Local Institution - 0077, Indianapolis

49565

NOT_YET_RECRUITING

Local Institution - 0001, Bramsche

55101

NOT_YET_RECRUITING

Local Institution - 0237, Mainz

55128

NOT_YET_RECRUITING

Local Institution - 0115, Mainz

58453

NOT_YET_RECRUITING

Local Institution - 0117, Witten

60077

NOT_YET_RECRUITING

Local Institution - 0138, Skokie

60590

NOT_YET_RECRUITING

Local Institution - 0130, Frankfurt am Main

60614

NOT_YET_RECRUITING

Local Institution - 0395, Chicago

64460

NOT_YET_RECRUITING

Local Institution - 0113, Monterrey

NOT_YET_RECRUITING

Local Institution - 0469, Monterrey

67100

NOT_YET_RECRUITING

Local Institution - 0269, L’Aquila

69120

NOT_YET_RECRUITING

Local Institution - 0106, Heidelberg

70006

RECRUITING

Clinical Trials Management, Metairie

70112

NOT_YET_RECRUITING

Local Institution - 0069, New Orleans

70433

NOT_YET_RECRUITING

Local Institution - 0449, Covington

70605

RECRUITING

Shondra L. Smith, MD - Dermatology and Advanced Aesthetics, Lake Charles

72076

NOT_YET_RECRUITING

Local Institution - 0260, Tübingen

75390

NOT_YET_RECRUITING

Local Institution - 0468, Dallas

76011

NOT_YET_RECRUITING

Local Institution - 0057, Arlington

77429

RECRUITING

Studies in Dermatology, LLC, Cypress

77598

RECRUITING

Center For Clinical Studies, Webster

78218

NOT_YET_RECRUITING

Local Institution - 0083, San Antonio

79104

NOT_YET_RECRUITING

Local Institution - 0101, Freiburg im Breisgau

80131

NOT_YET_RECRUITING

Local Institution - 0249, Naples

85032

NOT_YET_RECRUITING

Local Institution - 0169, Phoenix

85254

WITHDRAWN

Local Institution - 0322, Scottsdale

85255

WITHDRAWN

Local Institution - 0188, Scottsdale

85260

NOT_YET_RECRUITING

Local Institution - 0432, Scottsdale

87700

NOT_YET_RECRUITING

Local Institution - 0112, Memmingen

88045

NOT_YET_RECRUITING

Local Institution - 0473, Friedrichshafen

89129

NOT_YET_RECRUITING

Local Institution - 0127, Langenau

89145

NOT_YET_RECRUITING

Local Institution - 0454, Las Vegas

90045

RECRUITING

Dermatology Research Associates - Howard Sofen, MD, Los Angeles

91054

NOT_YET_RECRUITING

Local Institution - 0200, Erlangen

91101

NOT_YET_RECRUITING

Local Institution - 0420, Pasadena

91325

RECRUITING

Northridge Clinical Trials - Elite Clinical Network, Northridge

91355

NOT_YET_RECRUITING

Local Institution - 0427, Santa Clarita

91767

NOT_YET_RECRUITING

Local Institution - 0387, Pomona

92647

RECRUITING

Marvel Clinical Research, Huntington Beach

93551

NOT_YET_RECRUITING

Local Institution - 0426, Palmdale

95815

NOT_YET_RECRUITING

Local Institution - 0316, Sacramento

95816

NOT_YET_RECRUITING

Local Institution - 0038, Sacramento

97070

NOT_YET_RECRUITING

Local Institution - 0118, Mérida

97210

RECRUITING

Oregon Dermatology and Research Center, Portland

100050

NOT_YET_RECRUITING

Local Institution - 0050, Beijing

100191

NOT_YET_RECRUITING

Local Institution - 0140, Beijing

110001

NOT_YET_RECRUITING

Local Institution - 0054, Shenyang

130021

WITHDRAWN

Local Institution - 0417, Changchun

150081

NOT_YET_RECRUITING

Local Institution - 0293, Harbin

200440

NOT_YET_RECRUITING

Local Institution - 0405, Craiova

210029

WITHDRAWN

Local Institution - 0401, Nanjing

210031

NOT_YET_RECRUITING

Local Institution - 0356, Zhenjiang

233017

NOT_YET_RECRUITING

Local Institution - 0352, Bengbu

250012

NOT_YET_RECRUITING

Local Institution - 0194, Jinan

250022

WITHDRAWN

Local Institution - 0108, Jinan

300757

NOT_YET_RECRUITING

Local Institution - 0441, Timișoara

310006

NOT_YET_RECRUITING

Local Institution - 0044, Hangzhou

310009

NOT_YET_RECRUITING

Local Institution - 0277, Hangzhou

NOT_YET_RECRUITING

Local Institution - 0051, Hangzhou

350005

NOT_YET_RECRUITING

Local Institution - 0049, Fuzhou

410011

WITHDRAWN

Local Institution - 0207, Changsha Shi

430022

NOT_YET_RECRUITING

Local Institution - 0047, Wuhan

430030

NOT_YET_RECRUITING

Local Institution - 0046, Wuhan

430031

NOT_YET_RECRUITING

Local Institution - 0414, Wuhan

450003

NOT_YET_RECRUITING

Local Institution - 0439, Zhengzhou

500285

NOT_YET_RECRUITING

Local Institution - 0225, Brasov

510000

NOT_YET_RECRUITING

Local Institution - 0353, Guangzhou

518052

NOT_YET_RECRUITING

Local Institution - 0386, Shenzhen

518058

NOT_YET_RECRUITING

Local Institution - 0129, Shenzhen

545300

NOT_YET_RECRUITING

Local Institution - 0388, Reghin

610021

NOT_YET_RECRUITING

Local Institution - 0354, Chengdu

610041

WITHDRAWN

Local Institution - 0053, Chengdu

630014

NOT_YET_RECRUITING

Local Institution - 0226, Chongqing

700401

NOT_YET_RECRUITING

Local Institution - 0403, Iași

707020

NOT_YET_RECRUITING

Local Institution - 0458, Iași

813414

NOT_YET_RECRUITING

Local Institution - 0315, Zuoying Dist

900591

NOT_YET_RECRUITING

Local Institution - 0398, Constanța

2542577

NOT_YET_RECRUITING

Local Institution - 0463, Viña del Mar

4701192

NOT_YET_RECRUITING

Local Institution - 0451, Toyoake Shi

5202192

NOT_YET_RECRUITING

Local Institution - 0452, Ōtsu

7580206

NOT_YET_RECRUITING

Local Institution - 0462, Santiago

7640881

NOT_YET_RECRUITING

Local Institution - 0461, Santiago

8420383

NOT_YET_RECRUITING

Local Institution - 0459, Santiago

85006-2722

NOT_YET_RECRUITING

Local Institution - 0107, Phoenix

72703-6245

NOT_YET_RECRUITING

Local Institution - 0335, Fayetteville

90056-1660

NOT_YET_RECRUITING

Local Institution - 0192, Los Angeles

92123-1523

WITHDRAWN

Local Institution - 0078, San Diego

94598-3335

NOT_YET_RECRUITING

Local Institution - 0181, Walnut Creek

30305-2515

NOT_YET_RECRUITING

Local Institution - 0434, Atlanta

02135

RECRUITING

Metro Boston Clinical Partners, Brighton

01757

NOT_YET_RECRUITING

Local Institution - 0409, Milford

02169-4339

WITHDRAWN

Local Institution - 0287, Quincy

48038-1137

NOT_YET_RECRUITING

Local Institution - 0329, Clinton Township

65201-6625

NOT_YET_RECRUITING

Local Institution - 0433, Columbia

68114-2508

WITHDRAWN

Local Institution - 0397, Omaha

89030-7193

NOT_YET_RECRUITING

Local Institution - 0396, North Las Vegas

03801

NOT_YET_RECRUITING

Local Institution - 0097, Portsmouth

NOT_YET_RECRUITING

Local Institution - 0460, Portsmouth

07666

WITHDRAWN

Local Institution - 0079, Teaneck

07044

NOT_YET_RECRUITING

Local Institution - 0359, Verona

10956-7153

NOT_YET_RECRUITING

Local Institution - 0393, New City

10029-6574

WITHDRAWN

Local Institution - 0410, New York

28602-1469

NOT_YET_RECRUITING

Local Institution - 0406, Hickory

43209-2421

WITHDRAWN

Local Institution - 0177, Bexley

43110-2069

WITHDRAWN

Local Institution - 0392, Canal Winchester

44256-9312

NOT_YET_RECRUITING

Local Institution - 0436, Medina

97504-7738

NOT_YET_RECRUITING

Local Institution - 0394, Medford

17011-2308

RECRUITING

Best Skin Research, Camp Hill

57702-9208

NOT_YET_RECRUITING

Local Institution - 0084, Rapid City

37072-2301

NOT_YET_RECRUITING

Local Institution - 0407, Goodlettsville

37205-1565

NOT_YET_RECRUITING

Local Institution - 0408, Nashville

C1060ABN

WITHDRAWN

Local Institution - 0429, Buenos Aires

C1055AAO

NOT_YET_RECRUITING

Local Institution - 0032, Buenos Aires

C1126AAB

NOT_YET_RECRUITING

Local Institution - 0034, Ciudad Autonoma Buenos Aires

C1425DKG

NOT_YET_RECRUITING

Local Institution - 0043, Ciudad Autonoma Buenos Aires

C1120AAF

NOT_YET_RECRUITING

Local Institution - 0474, Buenos Aires

X5000

NOT_YET_RECRUITING

Local Institution - 0455, Córdoba

36010-570

NOT_YET_RECRUITING

Local Institution - 0037, Juiz de Fora

80230-130

NOT_YET_RECRUITING

Local Institution - 0416, Curitiba

80730-380

NOT_YET_RECRUITING

Local Institution - 0384, Curitiba

58040-020

NOT_YET_RECRUITING

Local Institution - 0385, João Pessoa

90410-000

NOT_YET_RECRUITING

Local Institution - 0390, Porto Alegre

90560-032

NOT_YET_RECRUITING

Local Institution - 0036, Porto Alegre

18618-686

NOT_YET_RECRUITING

Local Institution - 0399, Botucatu

13086-888

NOT_YET_RECRUITING

Local Institution - 0383, Campinas

14051-140

NOT_YET_RECRUITING

Local Institution - 0193, Ribeirão Preto

15090-000

NOT_YET_RECRUITING

Local Institution - 0400, São José do Rio Preto

04038-002

NOT_YET_RECRUITING

Local Institution - 0490, Vila Clementino

01323-020

NOT_YET_RECRUITING

Local Institution - 0039, São Paulo

04075-000

NOT_YET_RECRUITING

Local Institution - 0450, São Paulo

T1Y 0B4

NOT_YET_RECRUITING

Local Institution - 0013, Calgary

T2G 1B1

NOT_YET_RECRUITING

Local Institution - 0126, Calgary

T6G 1C3

NOT_YET_RECRUITING

Local Institution - 0014, Edmonton

T6H 4J8

NOT_YET_RECRUITING

Local Institution - 0491, Edmonton

V1W 4V5

NOT_YET_RECRUITING

Local Institution - 0497, Kelowna

V9V 1A3

NOT_YET_RECRUITING

Local Institution - 0431, Nanaimo

V3R 6A7

NOT_YET_RECRUITING

Local Institution - 0120, Surrey

A1E 1V4

NOT_YET_RECRUITING

Local Institution - 0098, St. John's

L4M 7G1

RECRUITING

SimcoDerm Medical and Surgical Dermatology Center, Barrie

L8N 1Y2

NOT_YET_RECRUITING

Local Institution - 0005, Hamilton

N6A 5R9

NOT_YET_RECRUITING

Local Institution - 0430, London

L3P 1X3

NOT_YET_RECRUITING

Local Institution - 0300, Markham

L4Y 4C5

RECRUITING

DermEdge, Mississauga

P1B 3Z7

NOT_YET_RECRUITING

Local Institution - 0489, North Bay

L6J 7W5

NOT_YET_RECRUITING

Local Institution - 0498, Oakville

K1K 4L2

NOT_YET_RECRUITING

Local Institution - 0003, Ottawa

L4B 1A5

NOT_YET_RECRUITING

Local Institution - 0488, Richmond Hill

M3H 5Y8

NOT_YET_RECRUITING

Local Institution - 0173, Toronto

H1Y 3L1

NOT_YET_RECRUITING

Local Institution - 0464, Montreal

G1W 4R4

NOT_YET_RECRUITING

Local Institution - 0017, Québec

J1G 1X9

NOT_YET_RECRUITING

Local Institution - 0477, Sherbrooke

050030

NOT_YET_RECRUITING

Local Institution - 0438, Shijiazhuang

030001

NOT_YET_RECRUITING

Local Institution - 0055, Taiyuan

100 34

NOT_YET_RECRUITING

Local Institution - 0202, Prague

656 91

WITHDRAWN

Local Institution - 0440, Brno

779 00

WITHDRAWN

Local Institution - 0151, Olomouc

110 00

NOT_YET_RECRUITING

Local Institution - 0389, Prague

130 00

NOT_YET_RECRUITING

Local Institution - 0121, Prague

401 13

NOT_YET_RECRUITING

Local Institution - 0150, Ústí nad Labem

06000

NOT_YET_RECRUITING

Local Institution - 0153, Nice

06484

NOT_YET_RECRUITING

Local Institution - 0245, Quedlinburg

01307

NOT_YET_RECRUITING

Local Institution - 0255, Dresden

04103

WITHDRAWN

Local Institution - 0382, Leipzig

01097

NOT_YET_RECRUITING

Local Institution - 0109, Dresden

06108

NOT_YET_RECRUITING

Local Institution - 0472, Halle

00168

NOT_YET_RECRUITING

Local Institution - 0309, Roma

078-8510

NOT_YET_RECRUITING

Local Institution - 0374, Asahikawa-shi

565-0871

WITHDRAWN

Local Institution - 0378, Suita

WITHDRAWN

Local Institution - 0377, Suita-shi

501-1194

WITHDRAWN

Local Institution - 0376, Gifu

173-8605

NOT_YET_RECRUITING

Local Institution - 0391, Itabashi-Ku

920-8641

NOT_YET_RECRUITING

Local Institution - 0375, Kanazawa

830-0011

NOT_YET_RECRUITING

Local Institution - 0379, Kurume, Fukuoka

700-8558

NOT_YET_RECRUITING

Local Institution - 0456, Okayama

593-8324

NOT_YET_RECRUITING

Local Institution - 0380, Sakaishi

WITHDRAWN

Local Institution - 0415, Sakaishi

87-100

NOT_YET_RECRUITING

Local Institution - 0265, Torun

24-100

WITHDRAWN

Local Institution - 0425, Puławy

03-291

NOT_YET_RECRUITING

Local Institution - 0424, Warsaw

35-055

NOT_YET_RECRUITING

Local Institution - 0252, Rzeszów

15-375

NOT_YET_RECRUITING

Local Institution - 0292, Bialystok

40-081

NOT_YET_RECRUITING

Local Institution - 0195, Katowice

10-117

NOT_YET_RECRUITING

Local Institution - 0423, Olsztyn

60-309

NOT_YET_RECRUITING

Local Institution - 0428, Poznan

15-351

NOT_YET_RECRUITING

Local Institution - 0296, Bialystok

80-546

NOT_YET_RECRUITING

Local Institution - 0091, Gdansk

81-338

NOT_YET_RECRUITING

Local Institution - 0444, Gdynia

40-040

NOT_YET_RECRUITING

Local Institution - 0162, Katowice

40-611

NOT_YET_RECRUITING

Local Institution - 0154, Katowice

90-265

NOT_YET_RECRUITING

Local Institution - 0276, Lodz

43-190

NOT_YET_RECRUITING

Local Institution - 0413, Mikołów

96-100

NOT_YET_RECRUITING

Local Institution - 0421, Skierniewice

02-951

NOT_YET_RECRUITING

Local Institution - 0308, Warsaw

51-685

NOT_YET_RECRUITING

Local Institution - 0205, Wroclaw

25-316

NOT_YET_RECRUITING

Local Institution - 0244, Kielce

00725

NOT_YET_RECRUITING

Local Institution - 0475, Caguas

011464

NOT_YET_RECRUITING

Local Institution - 0412, Bucharest

020125

NOT_YET_RECRUITING

Local Institution - 0402, Bucharest

03722

NOT_YET_RECRUITING

Local Institution - 0060, Seoul

506 30

NOT_YET_RECRUITING

Local Institution - 0223, Borås

HP11 2QW

NOT_YET_RECRUITING

Local Institution - 0443, High Wycombe

KY12 0SU

NOT_YET_RECRUITING

Local Institution - 0284, Dunfermline

N12 8BU

NOT_YET_RECRUITING

Local Institution - 0442, London

SO16 6YD

NOT_YET_RECRUITING

Local Institution - 0274, Southampton

E11 1NR

NOT_YET_RECRUITING

Local Institution - 0241, London

N6A 2C2

NOT_YET_RECRUITING

Local Institution - 0004, London

M6 8HD

NOT_YET_RECRUITING

Local Institution - 0297, Salford

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT07116967 - Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK) | Biotech Hunter | Biotech Hunter