A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

PHASE1RecruitingINTERVENTIONAL
Enrollment

125

Participants

Timeline

Start Date

September 4, 2025

Primary Completion Date

February 13, 2029

Study Completion Date

August 16, 2030

Conditions
Refractory Autoimmune Diseases
Interventions
GENETIC

BMS-986515

Specified dose on specified days

DRUG

Fludarabine

Specified dose on specified days

DRUG

Cyclophosphamide

Specified dose on specified days

DRUG

Tocilizumab

Specified dose on specified days

Trial Locations (29)

0

NOT_YET_RECRUITING

Local Institution - 0039, Porto Alegre

2050

NOT_YET_RECRUITING

Local Institution - 0007, Camperdown

3168

NOT_YET_RECRUITING

Local Institution - 0013, Clayton

4029

NOT_YET_RECRUITING

Local Institution - 0008, Brisbane

10117

NOT_YET_RECRUITING

Local Institution - 0022, Berlin

12850

NOT_YET_RECRUITING

Local Institution - 0001, Prague

20246

NOT_YET_RECRUITING

Local Institution - 0031, Hamburg

24105

RECRUITING

Universitaetsklinikum Schleswig-Holstein Campus Kiel, Kiel

28034

RECRUITING

Hospital Universitario Ramón y Cajal, Madrid

40225

NOT_YET_RECRUITING

Local Institution - 0023, Düsseldorf

59037

NOT_YET_RECRUITING

Local Institution - 0006, Lille

67098

NOT_YET_RECRUITING

Local Institution - 0005, Strasbourg

98104

NOT_YET_RECRUITING

Local Institution - 0033, Seattle

400015

RECRUITING

ARENSIA Exploratory Medicine, Cluj-Napoca

5262100

RECRUITING

Sheba Medical Center, Ramat Gan

9112001

NOT_YET_RECRUITING

Local Institution - 0016, Jerusalem

02215

NOT_YET_RECRUITING

Local Institution - 0041, Boston

27705-2771

NOT_YET_RECRUITING

Local Institution - 0037, Durham

41253-190

NOT_YET_RECRUITING

Local Institution - 0040, Salvador

01508-010

NOT_YET_RECRUITING

Local Institution - 0038, São Paulo

150 06

NOT_YET_RECRUITING

Local Institution - 0004, Prague

01307

NOT_YET_RECRUITING

Local Institution - 0029, Dresden

80-952

NOT_YET_RECRUITING

Local Institution - 0019, Gdansk

41-902

RECRUITING

Szpital Specjalistyczny nr 1 w Bytomiu, Bytom

44-100

RECRUITING

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy w Gliwicach, Gliwice

93-513

NOT_YET_RECRUITING

Local Institution - 0017, Lodz

022328

RECRUITING

Fundeni Clinical Institute, Bucharest

08035

NOT_YET_RECRUITING

Local Institution - 0011, Barcelona

08041

NOT_YET_RECRUITING

Local Institution - 0009, Barcelona

All Listed Sponsors
lead

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

INDUSTRY

NCT07115745 - A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases | Biotech Hunter | Biotech Hunter