Exploring the Efficacy of Accelerated Transcranial Direct Current Stimulation (tDCS) as Adjunct to Pharmacotherapy in the Treatment of Obsessive-compulsive Disorder

NANot yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

August 11, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
DEVICE

high-definition transcranial direct current stimulation

The tDCS device will deliver a direct current of 2mA during 20 minutes. Cathode electrode will be localized in front of the right OFC on the Fp2 point according to the EEG international reference. Four anode electrodes will be placed around FP2 (i.e. Fpz, AFz, AF4, AF8)

DEVICE

Sham tDCS

To demonstrate the same stimulation sensation as under real conditions, only 40 seconds of real stimulation (2mA) are given at the beginning of the treatment. In the remaining 20 minutes, only about 15ms of short current pulses of 110uA occur every 550ms.

Trial Locations (1)

Unknown

Shanghai Mental Health Center, Shanghai

All Listed Sponsors
lead

Shanghai Mental Health Center

OTHER

NCT07115615 - Exploring the Efficacy of Accelerated Transcranial Direct Current Stimulation (tDCS) as Adjunct to Pharmacotherapy in the Treatment of Obsessive-compulsive Disorder | Biotech Hunter | Biotech Hunter