Effect of Combined Probiotics and Vitamin D on Symptoms of Allergic Rhinitis

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

August 1, 2025

Primary Completion Date

October 30, 2025

Study Completion Date

November 30, 2025

Conditions
Allergic RhinitisAllergic Rhinitis (AR)
Interventions
DRUG

Standard Allergic Rhinitis Treatment

Participants will receive standard-of-care treatment for allergic rhinitis, including oral antihistamines and/or intranasal corticosteroids, according to current clinical guidelines. No additional supplementation will be provided in the control group. This arm serves as the comparator for evaluating the effects of probiotic and vitamin D supplementation

DIETARY_SUPPLEMENT

Combined Vitamin D and Probiotics Supplementation

Participants in this group will receive a combination therapy of Vitamin D3 plus a daily oral probiotic capsule containing a standardized blend of Lactobacillus and Bifidobacterium species. Both supplements will be administered once daily for 12 weeks. This intervention aims to assess the synergistic effect of vitamin D and probiotics on immune response and symptom relief in allergic rhinitis.

Trial Locations (1)

Unknown

RECRUITING

Tanta University Hospital, ENT Department, Tanta

All Listed Sponsors
lead

Tanta University

OTHER