Ultrasound Guided Fluid Loading Before Spinal Anesthesia

PHASE4CompletedINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

May 1, 2024

Primary Completion Date

December 1, 2024

Study Completion Date

March 25, 2025

Conditions
Cesarean Section ComplicationsSpinal AnesthesiaHypotensionHypovolemiaSympathetic BlockadeFluid Loading
Interventions
DRUG

C

isotonic saline solution infusion (fluid preloading) to achieve correction of hypovolemia before spinal anesthesia using cardiac ultrasoud guidance by measurment of VTI variation after a 250ml saline solution loading, with a maximum of 4 challenges, until hypovolemia complete correction

DRUG

T

"isotonic saline solution coloading after spinal anesthesia associated with recsue boluses of Ephedrine would be the standard of care in this arm. No correction of hypovolemia is done before spinal anesthesia. parturients receive a cristalloid coloading with saline isotonic solution with rescue boluses of ephedrine if hypotesion happens after spinal anesthesia"

Trial Locations (1)

1007

Tunis maternity and neonatology center, minisetry of public health, Tunis

All Listed Sponsors
lead

University Tunis El Manar

OTHER

NCT07108881 - Ultrasound Guided Fluid Loading Before Spinal Anesthesia | Biotech Hunter | Biotech Hunter