Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries

NARecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

April 17, 2025

Primary Completion Date

April 1, 2027

Study Completion Date

April 1, 2027

Conditions
Intraoperative InfusionLidocaineDexmedetomidineCerebral Oxygen SaturationPostoperative DeliriumElderly PatientsAbdominal Surgeries
Interventions
DRUG

Lidocaine

Patients will receive an IV bolus (50 ml) of lidocaine (1mg/kg) diluted with saline over 10 min before induction of anesthesia. This will be followed by intraoperative lidocaine infusion in a dose of 1.5mg /kg/hr till the end of surgery.

DRUG

Dexmedetomidine

Patients will receive an IV bolus (50 ml) of dexmedetomidine in dose 0.5 μg/kg over 10 min before induction of anesthesia. This will be followed by intraoperative dexmedetomidine infusion in a dose of 0.3 μg/kg/hr till the end of surgery.

Trial Locations (1)

31527

RECRUITING

Tanta University, Tanta

All Listed Sponsors
lead

Tanta University

OTHER