Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS

NARecruitingINTERVENTIONAL
Enrollment

290

Participants

Timeline

Start Date

April 2, 2025

Primary Completion Date

August 31, 2026

Study Completion Date

November 30, 2026

Conditions
COPDSmokingTobacco Use
Interventions
OTHER

Cigarette

COPD patients will continue to smoke their cigarettes ad libitum, with no brand restrictions.

OTHER

THS

COPD patients will switch from cigarette smoking to ad libitum THS use, with no flavor variant restrictions.

Trial Locations (111)

1336

NOT_YET_RECRUITING

MHAT Lyulin EAD, Sofia

1510

NOT_YET_RECRUITING

Medical Center Hera EOOD, Sofia

1756

NOT_YET_RECRUITING

Medical Center Pulmovision Ltd, Sofia

2300

RECRUITING

MHAT Rahila Angelova, Pernik

3000

RECRUITING

SHATPPD Vratsa, Vratsa

4509

RECRUITING

Klifeck GmbH, Delitzsch

NOT_YET_RECRUITING

POIS Sachsen GmbH, Leipzig

5003

NOT_YET_RECRUITING

SHATPD Dr. Treyman, Veliko Tarnovo

5201

RECRUITING

Plucna ambulancia Hrebenar S.R.O., Spišská Nová Ves

10117

NOT_YET_RECRUITING

Klinische Forschung Berlin Mitte /Pratia Germany, Berlin

10717

RECRUITING

Research Center for Medical Studies, Berlin

11025

RECRUITING

Sana Medical Center, Bucharest

23858

NOT_YET_RECRUITING

Praxis Reinfeld Mitte, Reinfeld

30038

RECRUITING

Pivotal Research Solutions, Stonecrest

30159

NOT_YET_RECRUITING

Klinische Forschung Hannover-Mitte GmbH /Pratia Germany, Hanover

32713

NOT_YET_RECRUITING

Omega Research Debary, LLC, DeBary

32803

NOT_YET_RECRUITING

Central Florida Pulmonary Group, P.A., Orlando

33012

RECRUITING

Felicidad Med Research, Hialeah

33014

NOT_YET_RECRUITING

Pharma Medical Innovations, Miami Lakes

33015

RECRUITING

San Marcus Research, Miami Lakes

33016

RECRUITING

MedQuest Translational Sciences LLC, Miami Lakes

33021

NOT_YET_RECRUITING

The Medici Medical Research, LLC, Hollywood

33024

RECRUITING

Alfa Medical Research, Davie

33063

RECRUITING

D&H Pompano Research Center, Margate

33122

RECRUITING

D&H Doral Research Center, Doral

33125

RECRUITING

Med-Care Research Corp, Miami

33126

RECRUITING

EMDA Clincal Research, Miami

33133

RECRUITING

Sones Medical Research, Miami

33134

RECRUITING

Florida International Medical Research, Coral Gables

33135

NOT_YET_RECRUITING

Suncoast Research Group, LLC dba Flourish Research, Miami

33145

RECRUITING

Melgar-Caro Medcenter and Community Research, Miami

33155

RECRUITING

D&H National Research Center- Miami, Miami

33156

RECRUITING

Biomed Research & Medical Center.Llc, Miami

33162

NOT_YET_RECRUITING

Harmony Clinical Research, North Miami Beach

33165

RECRUITING

Global Health Clinical Trials Corp., Miami

33172

RECRUITING

Professional Research Center Inc, Miami

33176

RECRUITING

Newgen Health Group, Miami

RECRUITING

Reserka LLC, Miami

33317

NOT_YET_RECRUITING

Comprehensive Medical & Research Center, Plantation

33321

RECRUITING

D&H Tamarac Research Center, Tamarac

NOT_YET_RECRUITING

Metropolitan Clinical Research Center, Tamarac

33612

RECRUITING

Optimum Clinical Trial Group, Tampa

33710

NOT_YET_RECRUITING

Advanced Research Institute, Inc, St. Petersburg

33765

NOT_YET_RECRUITING

Clinical Research of West Florida, Inc., Clearwater

34653

RECRUITING

Advanced Research Institute, Inc, New Port Richey

34952

NOT_YET_RECRUITING

CDC Research Institute, Port Saint Lucie

34986

RECRUITING

Treasure Coast Medical Research Group, Port Saint Lucie

58452

RECRUITING

Lungenpraxis Witten, Witten

63065

RECRUITING

FutureMeds Frankfurt, Offenbach

63263

NOT_YET_RECRUITING

Ballenberger Freytag Wenisch - Institut für klinische Forschung GmbH, Neu-Isenburg

65183

NOT_YET_RECRUITING

BAG Peter Fried / Dr. med. Roman Rubin, Wiesbaden

65189

NOT_YET_RECRUITING

Velocity Clinical Research Wiesbaden, Wiesbaden

75020

NOT_YET_RECRUITING

Premier Pulmonary Critical Care and Sleep Medicine, Denison

75069

NOT_YET_RECRUITING

Metroplex Pulmonary & Sleep Center, McKinney

75092

NOT_YET_RECRUITING

Medrasa Clinical Research, Sherman

75165

RECRUITING

Pulmonics Plus, Waxahachie

76137

NOT_YET_RECRUITING

Klinische Forschung Karlsruhe GmbH / Pratio Germany, Karlsruhe

77022

NOT_YET_RECRUITING

HDH Research Inc, Houston

77054

NOT_YET_RECRUITING

Prolato Research LLC., Houston

77089

RECRUITING

Houston Pulmonary Medicine Associates, Houston

77099

RECRUITING

Pioneer Research Solutions Inc, Houston

77338

RECRUITING

Accurate Clinical Research, Inc., Humble

78258

RECRUITING

Element Research Group, San Antonio

79902

NOT_YET_RECRUITING

El Paso Pulmonary Association, El Paso

237143

RECRUITING

Clintrial Medical Centre SRL, Dobrosloveni

410163

RECRUITING

Spital de Pneumologie dr Lavinia Davidescu Oradea, Oradea

500440

NOT_YET_RECRUITING

Sc. Centrul Medical Sana Srl, Brasov

550082

NOT_YET_RECRUITING

AI Clinical Research, Sibiu

910103

NOT_YET_RECRUITING

Ames Research Center, Călăraşi

278 01

RECRUITING

MUDr. Otakar Hokynar - plicni ambulance, Kralupy nad Vltavou

779 00

NOT_YET_RECRUITING

Ordinace pro tbc a respirační nemoci s.r.o., Olomouc

702 00

NOT_YET_RECRUITING

CCR Ostrava s.r.o., Ostrava

140 00

RECRUITING

Medicon a.s., Prague

190 00

NOT_YET_RECRUITING

Prvni plicni ambulance s.r.o., Prague

407 47

NOT_YET_RECRUITING

Pneumologie Varnsdorf s.r.o., Varnsdorf

04157

NOT_YET_RECRUITING

Facharzt für Innere Medizin und Pneumologie, Leipzig

Unknown

RECRUITING

"Siteworks - Prüfzentrum Schleswig , RespiRatio"

812-0016

RECRUITING

Soejima Clinic, Fukuoka

964-0871

RECRUITING

JCHO Nihonmatsu Hospital, Fukushima

371-0054

RECRUITING

Maebashi North Hospital, Gunma

674-0063

RECRUITING

Akashi Medical Center, Hyōgo

104-0031

RECRUITING

Fukuwa Clinic, Tokyo

170-0003

RECRUITING

Kouwa Clinic, Tokyo

992-0045

RECRUITING

Sanyuudo Hospital, Yamagata

232-0064

RECRUITING

Yokohama Minoru Clinic, Yokohama

160-0004

RECRUITING

Clinical Research Hospital Tokyo, Yotsuya

15-044

RECRUITING

Centrum Medycyny Oddechowej Mroz Spolka jawna, Bialystok

05-830

NOT_YET_RECRUITING

BioResearch Group Sp. z.o.o, Kajetany

31-501

RECRUITING

FutureMeds Krakowskie Centrum Medyczne, Krakow

91-363

RECRUITING

FutureMeds Łódź, Lodz

91-495

NOT_YET_RECRUITING

AmiCare Centrum Medyczne, Lodz

96-500

NOT_YET_RECRUITING

RCMed Oddział Sochaczew, Sochaczew

00-215

NOT_YET_RECRUITING

FutureMeds Warszawa Centrum, Warsaw

03-291

NOT_YET_RECRUITING

FutureMeds Targówek, Warsaw

53-301

NOT_YET_RECRUITING

Dobrostan, Wroclaw

53-673

NOT_YET_RECRUITING

FutureMeds Wrocław, Wroclaw

077025

NOT_YET_RECRUITING

Ames Research Center, Bragadiru

040 01

NOT_YET_RECRUITING

PANACEUM s.r.o., Košice

NOT_YET_RECRUITING

Vseobecna ambulancia pre dospelych, Košice

080 01

NOT_YET_RECRUITING

Pulmo s.r.o.,, Prešov

955 01

RECRUITING

Alergia s. r. o., Topoľčany

EN3 4GS

NOT_YET_RECRUITING

Panthera Biopartners, Enfield

G51 4TF

NOT_YET_RECRUITING

Panthera Biopartners, Glasgow

HP11 2QW

NOT_YET_RECRUITING

Velocity High Wycombe, High Wycombe

IG1 4HP

NOT_YET_RECRUITING

4 Medical Clinical Solutions (4MCS), London

M27 8FF

NOT_YET_RECRUITING

4 Medical Clinical Solutions (4MCS), Manchester

CH62 6EE

NOT_YET_RECRUITING

FutureMeds Liverpool, Metropolitan Borough of Wirral

PR2 9QB

NOT_YET_RECRUITING

Panthera Biopartners, Preston

OL11 4AU

NOT_YET_RECRUITING

Panthera Biopartners, Rochdale

S2 5FX

NOT_YET_RECRUITING

Panthera Biopartners, Sheffield

YO24 4LJ

NOT_YET_RECRUITING

Panthera Biopartners, York

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