O2 Consumption And CO2 Production After Hemodynamic Optimization In Shock

RecruitingOBSERVATIONAL
Enrollment

36

Participants

Timeline

Start Date

July 29, 2025

Primary Completion Date

July 31, 2027

Study Completion Date

December 31, 2027

Conditions
Hemodynamic InstabilityOxygen Consumption (V̇O2)
Interventions
OTHER

Noradrenalin

"After inclusion, patients will be tested for fluid responsiveness. Pulse pressure variation (PPV) will be evaluated.~In case of PPV\> 13% a fluid bolus of 500 mL of Lactated Ringer's will be administered in 10 minutes.~If PPV\< 8% Norepinephrine will be administered or increased. If PPV is in the gray zone, a PLRT will be performed and if CO increases more than 10% a fluid bolus will be prescribed, otherwise norepinephrine increased."

OTHER

Fluid bolus

"After inclusion, patients will be tested for fluid responsiveness. Pulse pressure variation (PPV) will be evaluated.~In case of PPV\> 13% a fluid bolus of 500 mL of Lactated Ringer's will be administered in 10 minutes.~If PPV\< 8% Norepinephrine will be administered or increased. If PPV is in the gray zone, a PLRT will be performed and if CO increases more than 10% a fluid bolus will be prescribed, otherwise norepinephrine increased."

Trial Locations (1)

00168

RECRUITING

Policlinico Universitario Fondazione Agostino Gemelli IRCCS, Roma

All Listed Sponsors
lead

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

NCT07107724 - O2 Consumption And CO2 Production After Hemodynamic Optimization In Shock | Biotech Hunter | Biotech Hunter