Hybrid vs. Conventional Surgery for Type A Aortic Dissection

NACompletedINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

January 1, 2021

Primary Completion Date

March 30, 2023

Study Completion Date

March 30, 2023

Conditions
Acute Stanford Type A Aortic Dissection
Interventions
PROCEDURE

One-Stop Hybrid Surgery

With the patient under moderate hypothermia (approx. 28°C) and cardiopulmonary bypass, surgeons perform a total arch replacement using a standard 4-branched graft. After the open repair is complete, a separate, distinct covered stent graft is deployed antegradely into the descending aorta through the open distal end of the arch graft. Completion angiography confirms correct placement.

PROCEDURE

Conventional Total Arch Replacement with Frozen Elephant Trunk

With the patient under deep hypothermic circulatory arrest (23°C-25°C) and cardiopulmonary bypass, surgeons perform a total arch replacement using an integrated hybrid prosthesis (Frozen Elephant Trunk), which consists of a vascular graft sutured to a covered stent graft. This single device is deployed antegradely into the descending aorta, and the arch vessels are then reattached to the branches of the prosthetic graft.

Trial Locations (1)

050000

The Fourth Hospital of Hebei Medical University, Shijiazhuang

All Listed Sponsors
lead

The First Hospital of Hebei Medical University

OTHER

NCT07107711 - Hybrid vs. Conventional Surgery for Type A Aortic Dissection | Biotech Hunter | Biotech Hunter