20
Participants
Start Date
August 10, 2025
Primary Completion Date
August 1, 2027
Study Completion Date
August 1, 2029
Autologous hematopoietic stem cell transplantation
Patients receive transplantation conditioning followed by autologous hematopoietic stem cell transplantation after successful stem cell mobilization and collection.
BCMA CAR-T
Patients will receive BCMA CAR-T single dose (3.0 x 10\^6 cells /kg) infusion 3 days after ASCT.
GPRC5D/CD3 BiTEs
Patients will receive GPRC5D/CD3 BiTEs maintenance therapy at a dose of 54 μg/kg every 4 weeks, starting 3 months after BCMA CAR-T infusion and continuing for at least 2 years
RECRUITING
Institute of Hematology and Blood Diseases Hospital Chinese Academy of Medical Sciences, Tianjin
Institute of Hematology & Blood Diseases Hospital, China
OTHER