CEH-EUS for Differentiating GISTs and Leiomyomas: A Multicenter Prospective Self-Controlled Study

Not yet recruitingOBSERVATIONAL
Enrollment

288

Participants

Timeline

Start Date

August 31, 2025

Primary Completion Date

June 30, 2026

Study Completion Date

October 31, 2026

Conditions
Submucosal TumorGastrointestinal Stromal Tumor (GIST)Leiomyoma
Interventions
DIAGNOSTIC_TEST

Endoscopic Ultrasound

Conventional EUS will be performed to evaluate lesion size, echogenicity, border, and layer of origin for differentiation between GISTs and leiomyomas and risk stratification of GISTs.

DIAGNOSTIC_TEST

Contrast-Enhanced Harmonic Endoscopic Ultrasound (CEH-EUS)

CEH-EUS will be conducted using a contrast agent to assess vascularity and enhancement patterns of the lesion for differentiation between GISTs and leiomyomas and risk stratification of GISTs.

Trial Locations (1)

430030

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

All Listed Sponsors
collaborator

Zhongnan Hospital

OTHER

collaborator

Wuhan Central Hospital

OTHER

lead

Huazhong University of Science and Technology

OTHER

NCT07106411 - CEH-EUS for Differentiating GISTs and Leiomyomas: A Multicenter Prospective Self-Controlled Study | Biotech Hunter | Biotech Hunter