Biofiller and Gingival Phenotype Thickening

NARecruitingINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

July 30, 2025

Primary Completion Date

November 3, 2025

Study Completion Date

May 1, 2026

Conditions
Gingival RecessionGingival DiseasesGingival Inflammation
Interventions
PROCEDURE

Biofiller Injection

Biofiller will be prepared by heating the platelet-poor plasma (PPP) component obtained from peripheral blood, which is then mixed with concentrated PRF (c-PRF). After creating a surgical tunnel in the mandibular anterior region (canine to canine), 0.5 mL of the prepared biofiller will be injected into each tooth region under the gingiva. The procedure is performed under local anesthesia and aims to increase gingival thickness in patients with a thin periodontal phenotype.

PROCEDURE

connective tissue graft

A connective tissue graft will be harvested from the palatal donor site and placed under the gingiva using a minimally invasive tunneling technique in the mandibular anterior region (canine to canine). The procedure will be performed under local anesthesia and aims to increase gingival thickness. No biomaterials or adjunctive agents will be used.

Trial Locations (1)

44000

RECRUITING

Inonu university, Malatya

All Listed Sponsors
lead

Inonu University

OTHER

NCT07104019 - Biofiller and Gingival Phenotype Thickening | Biotech Hunter | Biotech Hunter