Phase I Study of Preconditioning Radiation Therapy With IL-15 Transduced TGFBR2 KO CAR.TROP2-engineered Cord Blood-derived NK Cells in Patients With Advanced Head and Neck Cancer (RADIANCE-NK)

PHASE1Not yet recruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

February 8, 2026

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2029

Conditions

Head and Neck Cancer

Interventions

DRUG

Fludarabine

Given by infusion

DRUG

Cyclophosphamide

Given by infusion

Trial Locations (1)

The University of Texas M. D. Anderson Cancer Center, Houston

All Listed Sponsors

lead

M.D. Anderson Cancer Center

OTHER