A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG

PHASE1/PHASE2Not yet recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
Coronary Artery DiseaseSystemic Inflammatory Response SyndromePostoperative Complications
Interventions
DRUG

Normal saline

After induction of anesthesia give 10 ml of normal saline then followed by infusion of normal saline till extubation of patient in ICU

DRUG

Dexmedetomidine

After induction of anesthesia give loading dose of precedex 1 mcg/kg diluted in 10 ml normal saline then attach syringe pump of precedex infusion of 0.5mcg/kg/hr till extubation in ICU

DRUG

Methylprednisolone

After induction of anesthesia give solumedrol of a dose 10mg/kg diluted in 10ml of normal saline followed by a normal saline infusion till the extubation of the patient in the ICU

Trial Locations (1)

Unknown

Ain Shams University, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT07101367 - A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG | Biotech Hunter | Biotech Hunter