NCT07099859View on ClinicalTrials.gov

Effect of Losartan on the Neurohumoral Axis and Ventricular Remodeling of Patients With Severe Aortic Regurgitation Undergoing Valve Surgery.

PHASE4RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

July 1, 2025

Primary Completion Date

July 1, 2029

Study Completion Date

July 1, 2029

Conditions
Heart Valve DiseasesLeft Ventricle RemodelingAortic Regurgitation DiseaseHeart Failure CongestiveNatriuretic Peptide, Brain
Interventions
DRUG

Losartan 50 mg

Losartan 50 mg per day

DRUG

Placebo

Placebo 1 pill per day

Trial Locations (1)

05403-000

RECRUITING

Heart Institute of the School of Medicine of the University of São Paulo, São Paulo

All Listed Sponsors
collaborator

Fundação de Amparo à Pesquisa do Estado de São Paulo

OTHER_GOV

lead

Vitor Emer Egypto Rosa

OTHER