"Ultrasound-Enhanced Propolis Therapy for Healing Diabetic Foot Wounds"

NANot yet recruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

September 30, 2025

Primary Completion Date

August 25, 2026

Study Completion Date

September 25, 2026

Conditions
Diabetic Foot Ulcer tType 1 Diabetes MellitusType 2 Diabetes MellitusWound ManagementChronic Wound Healing
Interventions
DEVICE

Sham ultrasound (placebo)

Participants will receive conventional wound care including debridement, cleaning, and dressing. A sham ultrasound device that emits no therapeutic waves will be applied to simulate the intervention procedure.

DRUG

Propolis gel (10%)

Participants will receive topical application of 10% propolis gel on the diabetic foot ulcer followed by therapeutic ultrasound (phonophoresis) using 1 MHz frequency, 0.5-1.5 W/cm² intensity, pulsed mode (20%), for 5 minutes per session, 3 sessions/week for 4 weeks.

All Listed Sponsors
lead

Sinai University

OTHER