Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

October 10, 2024

Primary Completion Date

October 10, 2025

Study Completion Date

December 31, 2025

Conditions
Postoperative PainNausea and Vomiting, PostoperativeDizzinessConstipationDuration of ResponseNarcotics ConsumptionPain After Surgery
Interventions
DRUG

Low, non-weight based dose of Dexamethasone and Dexmedetomidine in peripheral nerve blocks

Low, non-weight based dose of Dexamethasone and Dexmedetomidine adjunct with Ropivacaine (local anesthetic) for use in peripheral nerve blocks to look for synergistic effects of the combination in extending the duration of the block while limiting any potential side effects of each additive.

DRUG

Ropivacaine with low, non weight based Dexamethasone additive

Very accepted, standard peripheral nerve block with steroid adjunct solution used to increase the duration of local anesthetic by 4-6hrs.

Trial Locations (1)

85713

Banner - University Medical Center South, Tucson

All Listed Sponsors
lead

University of Arizona

OTHER

NCT07099222 - Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve Blocks | Biotech Hunter | Biotech Hunter