To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU.

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

March 12, 2025

Primary Completion Date

June 4, 2025

Study Completion Date

June 4, 2025

Conditions
TachycardiaHypertensionHypoxiaHyperventilationResidual Paralysis, Post Anesthesia
Interventions
DRUG

Placebo drug ( normal saline )

At the end of surgery patients will be given placebo ( normal saline ) instead of neostigmine ( reversal agent of atracurium ) , to observe Heart rate, blood pressure , respiratory rate and oxygen saturation on extubation and post operative airway reflexes and residual paralysis

DRUG

neostigmine (reversal agent)

At the end of surgery patients will be given neostigmine ( reversal agenr ) , to observe Heart rate, blood pressure , respiratory rate and oxygen saturation on extubation and post operative airway reflexes and residual paralysis

Trial Locations (1)

Unknown

Ziauddin university, Karachi

All Listed Sponsors
lead

Ziauddin University

OTHER

NCT07097441 - To Observe Haemodynamic Parameters Including, Heart Rate, Blood Pressure, Respiratory Rate , and Oxygen Saturation, With or Without Giving Reversal Agent on Extubation, in Patients Receiving Single Shot of Atracurium , and to Observe Post Operative Residual Paralysis and Airway Reflexes in PACU. | Biotech Hunter | Biotech Hunter