NCT07094685 - Ivonescimab Before Surgery for the Treatment of Resectable Stage II-IV Head and Neck Cancer | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

November 1, 2025

Primary Completion Date

August 1, 2027

Study Completion Date

November 1, 2030

Conditions

Advanced Head and Neck Squamous Cell CarcinomaResectable Head and Neck Squamous Cell CarcinomaStage II Head and Neck Cutaneous Squamous Cell CarcinomaStage III Head and Neck Cutaneous Squamous Cell CarcinomaStage IV Head and Neck Cutaneous Squamous Cell Carcinoma

Interventions

PROCEDURE

Biopsy Procedure

Undergo biopsy

PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Computed Tomography

Undergo PET-CT and CT scan

BIOLOGICAL

Ivonescimab

Given IV

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

PROCEDURE

Positron Emission Tomography

Undergo PET-CT scan

PROCEDURE

Surgical Procedure

Undergo surgical dissection

Trial Locations (1)

48109

University of Michigan Comprehensive Cancer Center, Ann Arbor