Quality Improvement Intervention for a Safe Antimicrobial Use Reduction in Critically Ill Patients

NARecruitingINTERVENTIONAL
Enrollment

9,000

Participants

Timeline

Start Date

June 1, 2025

Primary Completion Date

April 30, 2026

Study Completion Date

July 31, 2026

Conditions
InfectionAntimicrobial StewardshipCritically Ill Intensive Care Unit Patients
Interventions
OTHER

Educational Quality Improvement Intervention

The intervention will be delivered at the cluster level. It will include an initiation visit, when educational sessions and an operations manual will be delivered to the ICU. These will consist of cognitive aids for antimicrobial initiation and duration decision-making, based on recent recommendations from guidelines, societies and regulatory authorities. In this visit, an assessment of barriers and facilitators for implementation of the behavioral change will be done, so that local adaptations can be done by the clinicians championing the implementation. Additionally, monthly, one-day audits will be done, which will be used to provide feedback to the ICU during the intervention phase regarding the suggested recommendations for antimicrobial decision-making.

Trial Locations (10)

Unknown

RECRUITING

Hospital Maternidade São José, Colatina

RECRUITING

Santa Casa de Misericórdia de Passos, Passos

RECRUITING

Hospital Municipal de Maringá, Maringá

RECRUITING

Hospital da Restauração, Recife

RECRUITING

Hospital Pelópidas Silveira, Recife

NOT_YET_RECRUITING

Hospital Naval Marcílio Dias, Rio de Janeiro

RECRUITING

Hospital Onofre Lopes, Natal

RECRUITING

Hospital de Pronto Socorro, Porto Alegre

RECRUITING

Hospital Santa Cruz, Santa Cruz do Sul

RECRUITING

Santa Casa de Misericórdia de Barretos, Barretos

All Listed Sponsors
collaborator

Hospital do Coracao

OTHER

collaborator

Hospital Israelita Albert Einstein

OTHER

collaborator

Beneficência Portuguesa de São Paulo

OTHER

lead

Hospital Sirio-Libanes

OTHER