460
Participants
Start Date
March 6, 2025
Primary Completion Date
February 28, 2029
Study Completion Date
July 31, 2029
Laparoscopic or robotic LINX procedure
Participants randomised to laparoscopic or robotic magnetic sphincter augmentation (LINX procedure) will receive surgical treatment under general anaesthesia, with placement of the LINX device around the distal oesophagus. The LINX device comprises titanium beads with magnets in the centre.
Laparoscopic or robotic fundoplication
Participants randomised to laparoscopic or robotic fundoplication will receive surgical treatment for managing GORD including a total or partial fundic wrap behind or in front of the distal oesophagus and gastro-oesophageal junction.
RECRUITING
Guy's and St Thomas's NHS Foundation Trust, Guy's and St Thomas's Hospital, Oxford
RECRUITING
Imperial College Healthcare NHS Trust, St Mary's Hospital, Oxford
RECRUITING
Leeds Teaching Hospitals NHS Trust, St James's University Hospital, Oxford
RECRUITING
Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford
RECRUITING
University Hospital Southampton NHS Foundation Trust, Oxford
King's College London
OTHER
Imperial College London
OTHER
Oxford University Hospitals NHS Trust
OTHER
Guy's and St Thomas' NHS Foundation Trust
OTHER
University of Bristol
OTHER
University of Southampton
OTHER
University of Oxford
OTHER