Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries

NARecruitingINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

July 20, 2025

Primary Completion Date

October 20, 2025

Study Completion Date

October 20, 2025

Conditions
Mechanical VentilationLung Protective VentilationDriving Pressure
Interventions
DEVICE

Lung protective ventilation

The patient in this group will receive tidal volume at 6-8 ml/kg of ideal body weight with PEEP of 5 cm of H2O and plateau pressure will be kept less than 30cm of H2O.

DEVICE

Driving pressure guided ventilation

They will receive tidal volume of 6-8 ml/kg of ideal body weight and initial PEEP of 5 cm of water. Principal investigator will then incrementally increase PEEP by 2 cm of water till a value 15 cm of water PEEP is reached or Plateau pressure becomes equal to 30 cm of water or driving pressure starts to increase or there is change in any hemodynamics. Each incremental PEEP will last for 3 respiratory cycles before moving on to next value. PEEP value with lowest driving pressure will then be selected for the duration of surgical procedure

Trial Locations (1)

46000

RECRUITING

Benazir Bhutto Hospital, Rawalpindi

All Listed Sponsors
lead

Rawalpindi Medical College

OTHER

NCT07092943 - Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries | Biotech Hunter | Biotech Hunter