Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

December 17, 2024

Primary Completion Date

August 31, 2025

Study Completion Date

August 31, 2025

Conditions
LongevityGLP-1GeroscienceAging
Interventions
DRUG

Metformin

Increasing doses from 500mg/d to 2000mg/d metformin

DRUG

Rapamycin

Increasing doses from 1mg/wk to 6mg/wk rapamycin

DRUG

Naltrexone

Increasing doses from 1.5mg b.i.d. to 4.5mg b.i.d. low-dose naltrexone

DIETARY_SUPPLEMENT

Vitamin C

Placebo control - increasing doses from 250mg/d to 1000mg/d vitamin C (ascorbic acid)

Trial Locations (1)

60605

RECRUITING

AgelessRx, Chicago

Sponsors

Lead Sponsor

All Listed Sponsors
lead

AgelessRx

INDUSTRY

NCT07092618 - Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation | Biotech Hunter | Biotech Hunter