NCT07088523View on ClinicalTrials.gov

Traditional Chinese Medicine Intervention for Ischemic Cardiovascular Disease Comorbid With Diabetes Mellitus: An Efficacy Comparative Study

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

4,205

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2027

Conditions
Diabete MellitusIschemic Cardiovascular Disease
Interventions
DRUG

Xintong Oral Liquid (Sequential Phase)

Xintong Oral Liquid (Lunan Pharmaceutical), 10 mL tid po from week 5 to 52.

DRUG

Xintong Oral Liquid (Intensive Phase)

Xintong Oral Liquid (Lunan Pharmaceutical), 20 mL tid po for 4 weeks.

DRUG

TCM Syndrome Differentiation Decoction

Individualized herbal decoction based on TCM diagnosis (four diagnostic methods), administered for 14 days during intensive phase.

DRUG

Standard Treatment (Guideline-Based)

Combination therapy including: 1. Antiplatelet: aspirin 100 mg/day + clopidogrel 75 mg/day. 2. Lipid-lowering: atorvastatin 20 mg/day. 3. Antidiabetic: metformin 500 mg bid (max 2000 mg/day). \*Doses may be adjusted per local guidelines or patient tolerance.

Trial Locations (1)

510120

Guangdong Traditional Chinese Medicine Hospital, Guangzhou

All Listed Sponsors
lead

Guangzhou University of Traditional Chinese Medicine

OTHER