HFNO VERSUS BIPAP IN PREECLAMPTIC PATIENTS WITH ACUTE HYPOXAEMIC RESPIRATORY FAILURE

NACompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

April 1, 2022

Primary Completion Date

March 20, 2025

Study Completion Date

March 20, 2025

Conditions
HFNO vs BIPAPPreeclamptic Acute Hypoxaemic Respiratory Failure
Interventions
OTHER

High flow nasal oxygen

Patients in group I then received HFNO. The initial flow rate was adjusted to 50L/min and gradually reduced as tolerated by the patient. The humidification chamber temperature was set at 37°C and gradually reduced to the patient comfort. FiO2 was 100% and then gradually reduced over time according to improvement in oxygenation.

OTHER

non invasive BIPAP

Patients in group II received oxygen therapy via intermittent non- invasive positive pressure ventilation, BiPAP mode ventilator using a face mask. BiPAP settings were adjusted as follows: P (low) of 5cm H2O to 10cm H2O and an inspiratory pressure P (high) of 10-20cm H2O . FiO2 was adjusted to 100% and then gradually reduced over time according to improvement in oxygen saturation and PaO2/Fio2 ratio. Respiratory rate was adjusted from 10-12 at then changed according to patient´s respiratory effort and according to ABG.

Trial Locations (1)

Unknown

Faculty of Medicine, Alexandria University, Alexandria

All Listed Sponsors
lead

Alexandria University

OTHER