A Multicenter, Randomized, Double-Blind, Controlled Clinical Study of Minocycline for the Treatment of Retinitis Pigmentosa

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

July 15, 2025

Primary Completion Date

February 28, 2028

Study Completion Date

June 30, 2028

Conditions
Retinitis PigmentosaInherited Retinal DystrophyRetina Disorder
Interventions
DRUG

Minocycline 100mg

Capsules Minocycline 100mg po per day and placebo 100mg po per day for 12 months

DRUG

Minocycline 200mg

Capsules Minocycline 100mg po twice a day for 12 months

DRUG

Placebo

Capsules placebo 100mg po twice a day for 12 months

Trial Locations (1)

510060

Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou

All Listed Sponsors
lead

Zhongshan Ophthalmic Center, Sun Yat-sen University

OTHER