N Acetylcystene in Treatment of Radiotherapy Induced Oral Mucositis in Oral Cancer Patients

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 15, 2024

Primary Completion Date

March 9, 2025

Study Completion Date

March 9, 2025

Conditions
Oral Mucositis
Interventions
DRUG

N-acetylcysteine (NAC) spray

N-acetylcysteine (NAC) mucoadhesive nanoparticles in the form of spray 3 times daily for 6 weeks

DRUG

Conventional treatment

"topical anesthetics agents (BBC \[Benzocaine, Benzydamine, and Cetalkonium chloride\] oral spray - oracure gel), topical antifungal agents (Miconaz oral gel)\*, sodium bicarbonate mouth wash (Alkamsir sachets), ice chip,s and anti-inflammatory mouth wash.~(Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology \[MASCC/ISSO\] guidelines) 3 times daily for 6 weeks."

Trial Locations (1)

Unknown

Outpatient Clinic of Oral medicine Department, Faculty of Dentistry, Alexandria University, Egypt, Alexandria

All Listed Sponsors
lead

Hams Hamed Abdelrahman

OTHER

NCT07082621 - N Acetylcystene in Treatment of Radiotherapy Induced Oral Mucositis in Oral Cancer Patients | Biotech Hunter | Biotech Hunter