NCT07078032View on ClinicalTrials.gov

A Randomized Controlled Trial Evaluating the Effectiveness of a Novel Risk-Stratified Screening Strategy for Lung Cancer

NANot yet recruitingINTERVENTIONAL
Enrollment

60,000

Participants

Timeline

Start Date

July 31, 2025

Primary Completion Date

July 31, 2028

Study Completion Date

November 30, 2028

Conditions
Lung Cancer Screening
Interventions
DIAGNOSTIC_TEST

Prediction Model Arm

Lung cancer risk stratification via prediction model integrating: advanced age, lung cancer family history, personal cancer history, childhood coal exposure, asthma history, and food allergy history. High-risk individuals receive LDCT screening. Thoracic physicians guide management of screen-positive cases.

DIAGNOSTIC_TEST

Standard Screening Arm

Participants are screened based on NCCN guideline criteria. High-risk individuals receive LDCT screening. Thoracic physicians guide management of screen-positive cases.

All Listed Sponsors
lead

The First Affiliated Hospital of Guangzhou Medical University

OTHER