Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols

NARecruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

August 25, 2025

Primary Completion Date

July 15, 2027

Study Completion Date

December 15, 2027

Conditions
Periodontitis
Interventions
PROCEDURE

Scaling and Root Planing

Mechanical debridement of tooth surfaces using hand and ultrasonic instruments

DRUG

antibiotic prophylaxis

2g Amoxicillin given 1 hour prior to instrumentation

DEVICE

810nm Diode Laser

Laser applied at base of gingival pockets prior to mechanical debridement.

PROCEDURE

Air Polishing

air flow-based mechanical debridement with erythritol powder

Trial Locations (1)

Unknown

RECRUITING

Department of Periodontology, Dental School of Athens, Athens

All Listed Sponsors
lead

National and Kapodistrian University of Athens

OTHER

NCT07077122 - Evaluation of the Systemic Burden of Non-surgical Periodontal Therapy: A Randomized Clinical Trial on Five Different Treatment Protocols | Biotech Hunter | Biotech Hunter