Fasting-Mimicking Diet as an Adjunct to Neoadjuvant Chemotherapy for Hormone-Receptor-Positive Breast Cancer

NANot yet recruitingINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

July 12, 2025

Primary Completion Date

December 30, 2026

Study Completion Date

December 30, 2026

Conditions
Fasting-Mimicking DietBreast CancerNeoadjuvant Chemotherapy
Interventions
DIETARY_SUPPLEMENT

Fasting-mimicking diet (FMD) Group

The FMD will consist of a triweekly 4-day regimen of a plant-based, calorie-restricted (827± 100 kcal on day 1;637 ± 100 kcal on days 2-4), low-carbohydrate, low-protein diet. The FMD will be repeated up to a maximum of eight consecutive cycles. Participants receive the FMD for 2 days prior to and on the day and one day after each cycle of chemotherapy.

Trial Locations (1)

Unknown

Guangdong Provincial People's Hospital, Guangzhou

All Listed Sponsors
lead

Guangdong Provincial People's Hospital

OTHER