NCT07076485View on ClinicalTrials.gov

Shortening Adjuvant Photon and Proton Irradiation (SAPPHIRe-II): A 4 Cohort, Randomized, Phase II Multi-center Trial Evaluating Shorter Schedules of Adjuvant Regional Nodal Irradiation Among Women and Men With Node-positive and High-risk Node-negative Invasive Breast Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

768

Participants

Timeline

Start Date

August 19, 2025

Primary Completion Date

January 1, 2029

Study Completion Date

January 1, 2031

Conditions
Breast Cancer
Interventions
RADIATION

Ultrahypofractionated radiation

Given by infusion

RADIATION

Moderately hypofractionated radiation

Given by infusion

Trial Locations (1)

77030

RECRUITING

The University of Texas M. D. Anderson Cancer Center, Houston

All Listed Sponsors
lead

M.D. Anderson Cancer Center

OTHER

NCT07076485 - Shortening Adjuvant Photon and Proton Irradiation (SAPPHIRe-II): A 4 Cohort, Randomized, Phase II Multi-center Trial Evaluating Shorter Schedules of Adjuvant Regional Nodal Irradiation Among Women and Men With Node-positive and High-risk Node-negative Invasive Breast Cancer | Biotech Hunter | Biotech Hunter