Endotherapy and/or Extracorporeal Shockwave Lithotripsy for Painless Chronic Pancreatitis

NARecruitingINTERVENTIONAL
Enrollment

126

Participants

Timeline

Start Date

July 21, 2025

Primary Completion Date

August 1, 2027

Study Completion Date

August 1, 2027

Conditions
Painless Chronic Pancreatitis
Interventions
BEHAVIORAL

Lifestyle modifications

Lifestyle modifications primarily include quitting smoking and alcohol consumption, as well as engaging in physical exercise.

DRUG

Pancreatic enzyme (Pancreatin Enteric-coated Capsules or Oryz-Aspergillus Enzyme and Pancreatin Table), antidiabetic medicine(Acarbose , Metformin, Glimepirde Tablets, Insulin)

"This intervention involves the use of medications to control the pancreatic exocrine and endocrine dysfunction caused by chronic pancreatitis.~1. Pancreatic enzyme therapy: Patients will use pancreatic enzymes (pancreatin enteric-coated capsules or oryz-aspergillus enzyme and pancreatin tablets) to control the symptoms of exocrine pancreatic insufficiency.~2. Diabetes treatment: Patients with diabetes will also use antidiabetic medications (such as oral hypoglycemic drugs or insulin, depending on glycemic control needs)."

PROCEDURE

Endoscopic Retrograde Cholangiopancreatography (ERCP) and/or Extracorporeal Shockwave Lithotripsy (ESWL)

This intervention involves the application of endoscopic retrograde cholangiopancreatography (ERCP) and/or extracorporeal shockwave lithotripsy (ESWL), conducted in accordance with established clinical guidelines. The procedures are tailored to the individual patient's condition, which may include sphincterotomy, balloon dilation of pancreatic duct strictures, stone extraction, and stent placement as indicated. ESWL may be used prior to ERCP to fragment pancreatic duct stones, facilitating their removal.

Trial Locations (1)

200433

RECRUITING

Changhai Hospital, Shanghai

All Listed Sponsors
lead

Changhai Hospital

OTHER

NCT07074379 - Endotherapy and/or Extracorporeal Shockwave Lithotripsy for Painless Chronic Pancreatitis | Biotech Hunter | Biotech Hunter